Survival of adult patients with acute myeloid leukemia at the Hematology Department at Hospital Pablo Tobón Uribe between 2004 and 2010

Main Article Content

Laura María Díaz Correa
Camilo Alberto Madrid Muñoz
Juan Felipe Combariza Vallejo
Kenny Mauricio Gálvez Cárdenas
Viviana Olaya Colorado
Jorge Hernando Donado Gómez

Abstract

Objective: To describe survival of AML patients at Hospital Pablo Tobón Uribe (HPTU) between January 2004 and June 2010.


Methods: An observational-descriptive case series in AML patients diagnosed and treated at HPTU between 2004 and 2010.


Results: Fifty-three cases of AML, 62.2% women. The median age was 55 years. Median WBC at diagnosis was 9,300. 5 cases (9.43%) were secondary to myelodysplastic syndromes. 51 patients (96.22%) received chemotherapy. The most common treatment regimen was idarubicin plus cytarabine 7x3 in 39 patients (73.58%). 28 patients (52.8%) achieved complete response to induction chemotherapy. 3 patients underwent allogeneic transplantation. 5 patients died during induction, 3 of them over 60 years. The median overall survival was 348 days. The median disease-free survival was 404 days. The overall survival rate at one year was 49%.


Conclusions: Series of 53 adult patients with AML. We found similar overall survival times as those reported in previous studies worldwide.

Keywords:
leukemia, myeloid, acute, drug therapy, survival

Article Details

Author Biographies

Laura María Díaz Correa, Hospital Pablo Tobon Uribe

Hematologist Internist. Hematology Unit. Pablo Tobón Uribe Hospital. Medellin Colombia

Camilo Alberto Madrid Muñoz, Hospital Pablo Tobon Uribe

Hematologist Internist. Hematology Unit. Pablo Tobón Uribe Hospital. Medellin Colombia.

Juan Felipe Combariza Vallejo, Hospital Pablo Tobon Uribe

Hematologist Internist. Hematology Unit. Pablo Tobón Uribe Hospital. Medellin Colombia

Kenny Mauricio Gálvez Cárdenas, Hospital Pablo Tobon Uribe

Hematologist Internist. Hematology Unit. Pablo Tobón Uribe Hospital. Medellin Colombia.

Viviana Olaya Colorado, Hospital Pablo Tobon Uribe

nternist. Hematology Unit. Pablo Tobón Uribe Hospital. Medellin Colombia.

Jorge Hernando Donado Gómez, Hospital Pablo Tobon Uribe

Internist. Clinical epidemiologist. Pablo Tobón Uribe Hospital. Titular Professor, Universidad Pontificia Bolivariana. Medellin Colombia.

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