Coagulation and massive bleeding: new concepts
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Abstract
It is now accepted categorically that the main initiating event of blood coagulation is exposure of tissue factor (TF), which leads to the formation of the complex factor VIIa / TF that activates factors IX and X on the surface of cells expressing the FT, and finally the production of thrombin. Below is a detailed review of all aspects related to the new cell theory tries to explain in a more physiological all events that occur during the coagulation process and at the end some aspects of coagulation disorders in the trauma patient will be displayed.
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