From Widal seroagglutination to Polymerase Chain Reaction for the diagnosis of Salmonellosis

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Hugo Trujillo Soto

Abstract

A review of the Widal test (1896) and the polymerase chain reaction (PCR) method invented by Kary Banks Mullis (1983) for the diagnosis of typhoid fever is made. This is done due to the validation of this method in Medellin by Sánchez and Cardona. Biographies of Widal and Mullis, as well as the clinical manifestations of typhoid fever are also described.

Keywords:
Typhoid, Diagnosis, Widal Seroagglutination test, Polymerase Chain Reaction

Article Details

Author Biography

Hugo Trujillo Soto, Corporation for Biological Research (CIB)

Pediatrician, Researcher, Corporation for Biological Research (CIB). Medellin. Colombia. S.A.

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