Stroke and prothrombotic states in cancer patients: case report and literature review
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Abstract
Cerebrovascular disease is usually associated to cancer and problems of hypercoagulability, with literature reporting that approximately 15% of the patients with cancer develop cerebrovascular disease in the clinic course of the illness. Cancer and cerebrovascular disease are the second and the third cause of death in United States. Unfortunately the coexistence of cancer and its treatment increase the risk of cerebrovascular disease and the comorbility attenuate the morbility and the mortality. We presented the case of a patient that presented ischemic cerebrovascular disease in the right cerebellum with progression of neurological damage in the absent of vascular risk factors. For the continuous abdominal pain the patient has an ecography and for problems in the deglution, an endoscopy was performed to evaluate the need for a gastrectomy. The result of the test was the presence of gastric mass that was identified as a diffuse adenoma Borrman I. A literature review is performed.
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Nguyen T, Angelis L. Stroke in cancer patiens. Curr Neurol Neurosci Rep. 2006;6:187-192
Trousseau A. Phlegmasia alba dolens. En: Clinique Medicale de l’Hoˆtel-Dieu de Paris. Paris: Balliere ;1865. p.654 –712.
Cestari D, Weine D, Panageas K, Segal AZ. Deangelis LM. Stroke in patiens with cancer:Incidence and etiology. Neurology. 2004;62:2025-2
Arboix A.. Cerebrovascular disease in the cancer patient. Rev Neurol. 2000 Dec 16-31;31(12):1250-2.
Khaled S, Griffiths E, Streiff M. Nonbacterial thrombotic endocarditis in cancer patients: pathogenesis, diagnosis, and treatment. Oncologist. 2007;12;518- 523
Chaturvedi S, Ansell J, Recht L. Should cerebral ischemic events in cancer patients be considered a manifestation of hypercoagulability?. Stroke. 1994; 25:1215–1218.
Judy E, Garber. Oliva E. Case 28-1997— A 67-YearOld Woman with Increasing Neurologic Deficits and a History of Breast and Ovarian Cancer New England journal of medicine.
Newton HB. Neurologic complications of systemic cancer. Am Fam Physician. 1999; 59:878-886.
Kooiker JC, MacLean JM, Sumi SM. Cerebral embolism marantic endocarditis, and cancer. Arch Neurol. 1976 ; 33:260–264.
Behrendt CE, Ruiz RB. Cerebral ischemic events in patients with advanced lung or prostate cancer. Neuroepidemiology. 2005; 24:230–236.
Murata J, Sawamura Y, Takahashi A, et al. Intracerebral hemorrhage caused by a neoplastic aneurysm from small-cell lung carcinoma: case report. Neurosurgery. 1993; 32:124–126.
Graus F, Rogers LR, Posner JB. Cerebrovascular complicationsin patients with cancer. Medicine. 1985; 64:16–35.
Glass J, Hochberg FH, Miller DC. Intravascular lymphomatosis : a systemic disease with neurologicmanifestations. Cancer. 1993 ; 71:3156– 3164.
Madeline C, Levine R. Thrombophilias and Stroke: diagnosis, treatment, and prognosis. J Thromb Thrombolysis. 20(2) ; 113–126, 2005.
Birgitte H, Jerahme P, Richard L. Stroke in Young Adults and Children. Curr Neurol Neurosci Rep. 2001; 1:54–66.
Rogers L, Cho E, Kempin S, Posner J. Cerebral infarction from non-bacterial thrombotic endocarditis. Clinical and pathological study including the effects of anticoagulation. Am J Med. 1987; 83:746–756
Feinberg W, Swenson M. Cerebrovascular complications of L-asparaginase therapy. Neurology. 1988; 38:127– 133.
Mitchell L., Andrew M, Hanna K, et al. A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with Lasparaginase: results of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase (PARKAA) Study. Cancer. 2003; 97:508–516.
Finelli P, Schauer PK. Cerebral sinus thrombosis with tamoxifen. Neurology. 2001; 56:1113–1114.
Coplin W, Cochran MS, Levine S, Crawford S. Stroke after bone marrow transplantation: frequency, aetiologyand outcome. Brain. 2001; 124:1043–1051.