Nodular prurigo: case presentation
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Abstract
Hyde’s Nodular Prurigo is a chronic dermathosis characterized by extremely itchy papular and nodular lesions. Concerning it’s treatment, a number of topical, intralesional and systemic medicines, along with cryotherapy and phototherapy have been used, usually in a concomitant way. In spite of the various options, many treatments lack efficacy and there are no standardized protocols. This manuscript’s the presentation of a clinical case concerning a 22-year-old woman with disseminated lesions in an advanced stage in both upper and lower limbs. The patient developed an important (60%) evolution of the clinical picture in little time with the combination of not-so-aggressive dermatological treatments such as cryotherapy and capsaine plus an antidepressant such as trazodone. A short literature review is performed.
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Navarrete G, Medina D, Olguín G, Navarrete G, Medina D, Olguín G. Prúrigo Nodular de Hyde: presentación de un caso. Rev Cent Dermatol Pascua. 2004;13 (2).
Soter AN. Prurigo Nodularis en Fitzpatrick’s Dermatology in General Medicine. 6. ed. New York: McGraw-Hill; 2003. p. 1196 -97.
Sanpaio S, Rivitti EA. Dermatología. 2. ed. San Pablo, Brasil: Saunders; 2000. p. 213 – 14.
Johansson, et al. Increased nerve growth factor and tyrosine kinase like inmunoreactivities in Prurigo Nodularis. Arch Dermatologie Research 2000; 293: 614 – 19.
Braun F, Plewig W. Dermatologie und venerologie. 5. ed. Massachussetts : Blackwell; 2005. p. 418 – 20.
Atlas de eccema atopico. Philadelphia : Saunders ; s.f. p.59.
Grasa P, Marrón J, Martín J, Porta N, Navarro M, et al. Prúrigo Nodular de Hyde: a propósito de cinco casos observados en adultos y dos infantiles. Actas Dermo Sif 1983; 74:170-76.
McKenzie AW, Stubbing DG, Eloy BL. Prurigo Nodularis and gluten enteropathy. Br J Dermatol 1976; 95: 89-92.
Paus R, Schmelz M, Bíró T, Steinhoff M. Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Investig 2006; 116: 1173 – 83
Arenas R. Dermatología Atlas: Prúrigo Nodular de Hyde. 2. ed. México: McGrawHill Interamericana ; 1996. p. 70-71.
Harris B, Harris K, Penneys NS. Demostration by S-100 protein staining of increased numbers of nerves in the papillary dermis of patients with Prurigo Nodularis. J Am Acad Dermatol. 1992; 26: 56-58.
Johny MK. San Francisco. West J Med. December 1989 : 151 – 6.
Pendido P, Agüero C, Kriunis I. Thalidomide and analogous. Alergia e Inmunologia Clinica 2005; 36(2): 41-51.
Thomas L, Ducros B, Secchi T, Balme B, Moulin G. Successful treatment of adult’s Langerhans cell histiocytosis with thalidomide. Arch Dermatol. 1993; 129: 1261-64.
Maurer T, Poncelet A , Berger T. Thalidomide treatment for prurigo nodularis in humans. 2006.
Perri III AJ , Hsu S. A review of thalidomide’s history and current dermatological applications. Dermatology online Journal 9
John MK. Treating Compulsive Behaviors in Dermatology. West J Med. 2000; 155: 523.
Schneider G. Psychological factors in Prúrigo Nodularis. Br J Dermatol . 2006 ;154 : 61
Vega JA, García-Suárez O, Hannestad J, Pérez-Pérez M, Germanà A. Neurotrophins and the immune system anatomical. J Anat. 2003 July; 203(1): 1–19.
Iglesias DL, Guerra TA, Ortiz R. PL. Prúrigo tratado de dermatología. Medicina; 2000: 396 - 97.