Dry eye in patientes with rheumatoid arthritis

Main Article Content

Cristina María Chaverra Sandoval
Juan Esteban Valencia Ceballos
Carlos Alberto Restrepo Peláez

Abstract

Objective: to evaluate the prevalence of dry eye in a rheumatoid arthritis patient’s population.


Methods: observational,descriptive and transversal study in 153 rheumatoid arthritis patients. Were assessed the prevalence of dry eye by Schirmer test, rose bengal staining, fluorescein staining and tear break up time. The severity of dry eye was evaluated by the Ocular Surface Disease Index (OSDI).


Results: 92.8% of patients were female. Dry eye prevalence evaluated by Schirmer test type I was 26.3%, rose bengal staining 23.7%, fluorescein staining 52.9% and tear break up time 63.5%. In the assesment of visual function, we found mild visual impairment between 63% and 75% of dry eye patients.


Conclusions: dry eye is the most frecuent complication in rheumatoid arthritis patients; hence, it is important early detection and multidisciplinary approach. The OSDI is a valuable complement in the valoration of these patients. It has excellent reliability, validity, sensitivity and specificity.

Keywords:
arthritis, rheumatoid, dry eye syndrome, fluorescein, rose bengal

Article Details

Author Biographies

Cristina María Chaverra Sandoval, Pontifical Bolivarian University

Third year residents of Ophthalmology, Faculty of Medicine, Universidad Pontificia Bolivariana.

Juan Esteban Valencia Ceballos, Pontifical Bolivarian University

Third year residents of Ophthalmology, Faculty of Medicine, Universidad Pontificia Bolivariana.

Carlos Alberto Restrepo Peláez, Pontifical Bolivarian University

Ophthalmologist. Professor at the Pontificia Bolivariana University.

References

Pérez MV, Díaz de Álvarez C1 y P. Frecuencia de ojo seco y su correlación con un cuestionario sintomatológico en pacientes con artritis reumatoide. RFM. 2001 Jul ;24(2):145-150.

Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995;21:221-232

Lemp MA. Dry Eye (Keratoconjunctivitis sicca), Rheumatoid Artritis and Sjögren. Am J Ophthalmol. 2005;140(5):898-899.

Moss SE, Klein BE. Incidence of dry eye in an older population. Arch Ophthalmol. 2004;122:369-373.

Fujita M, Tsutomu I, Kurai T, Sakane M, Yoshino S, Takahashi H. Correlation between Dry Eye and Rheumatoid Artritis Activity. Am J Ophthalmol. 2005;140:808-813.

Lee AJ, Lee J, Saw SM, Gazzard G, Koh D, Widjaja D, et al. Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia. Br J Ophthalmol. 2002;86(12):1347-1351.

Schiffman RM, Christianson MD, Jacobsen G, Hirsch JD, Reis BL. Realibility and validity of the Ocular Surface Disease Index. Arch Ophthalmol. 2000;118:615-621.

World Health Organization, WHO Media Centre. Magnitude and Causes of Visual Impairment [Internet]. Geneva :OMS ; 2004. [Fecha de acceso

de junio de 2008]. Disponible en: http://www.who.int/mediacentre/ factsheets/fs282/en/index.html. 9. Shimazaki J. Definition and criteria of dry eye. Ganka. 1995;37:765-770.

Jabs D. Ocular manifestations of the Rheumatic diseases. Philadelphia: JB Lippincott; 1992.

Lansbury J. Quantitation of the activity of Rheumatoid Artritis. I. A method for recording its systemic manifestations. Am J Med Sci. 1956;231:616-621.

Mody GM, Hill JC, Meyers OL. Keratoconjunctivitis sicca in rheumatoid artritis. Clin Rheumatol. 1988;7:237- 241.

Ausayakhun S, Louthrenoo W, Aupapong S. Ocular diseases in patients with rheumatic diseases. J Med Assoc Thai. 2002;85:855-862.

Korb DR, Greiner JV, Herman J. Comparison of Fluorescein Break-up Time Measurement Reproducibility Using Standard Fluorescein Strips Versus the Dry Eye Test (DET) Method. Cornea. 2001;20(8):811-815.

Ishida R, Kojima T, Dogru M, Kaido M, Matsumoto Y, Tanaka M, et al. The Application of a New continuous Functional Visual Acuity Measurement System in Dry Eye Síndromes. Am J Ophthalmol. 2005;139:253- 258.

Most read articles by the same author(s)