Lemierre Syndrome: report of a variant complicated with thrombosis of cavernous sinus
Article Sidebar
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Downloads
Societal impact
Main Article Content
Abstract
Lemierre Syndrome is a clinical entity characterized by a septic trombophlebitis of the intern jugular vein with a secondary embolism, etiological agent in more than 80% of cases is Fusobacterium necrophorum, however, other microorganisms has been described and up to 12.8% of the cases have no microbiological isolation. This article describes a case of a young man with infected facial skin lesions, who developed a pharyngeal infection with thrombosis of left internal jugular vein and of the ipsilaterl cavernous sinus, plus septic pulmonary embolism and pericardia compromise, in this patient an isolation of a microbilogical agent was no possible and a complete resolution of the case was reached by antibiotic therapy.
Article Details
References
García F. Infección orofaríngea y sépsis: ¿una relación olvidada? Emergencias 2006;18:228-230
Chirinos JA, Garcia J, Alcaide ML, Toledo G, Baracco GJ, Lichtstein DM. Septic thrombophlebitis: diagnosis and management. Am J Cardiovasc Drugs 2006; 6:9-14.
Chirinos JA, Lichtstein D, Garcia J, Tamariz LJ. The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine 2002; 81:458-65.
Riordan T. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s syndrome. Clin Microbiol Rev 2007;20:622– 659
Dool H, Soetekouw R, Zanten M, Grooters E. Lemierre’s syndrome: three cases and a review. Eur Arch Otorhinolaryngol 2005;262:651–654
Iqbal M, Baring D, Addidle M, Murray C, Adams C. Lemierre syndrome: two cases and a review. Laryngoscope 2007;117:1605–1610
Ramirez S, Hild TG, Rudolph CN, Sty JR, Kehl SC, Havens P, et al. Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children’s Hospital. Pediatrics 2003;112(5):380-385
Riordan T, Wilson M. Lemierre’s syndrome: more than a historical curiosa. Postgrad Med J 2004; 80:328 –34.
Castro F, Kendall JL. Diagnosis of Lemierre syndrome by bedside emergency department ultrasound. J Emerg Med 2008; 8: 1-4.
Brooks I. Infectious caused by beta-lactamase producing Fusobacterium. Pediatr Infect Dis J 1993; 12:532- 533.
Duong M, Wenger J. Lemierre syndrome. Pediatr Emerg Care 2005; 21: 589-593
Boga C, Ozdogu H, Diri B, Oguzkurt L, Asma S, Yeral M. Lemierre syndrome variant: Staphylococcus with thrombosis of both the right splenic vein after the exploration. J Thromb Thrombolysis 2007; 23:151– 154.
Sherer Y, Mishal J. The changing face of Lemierre’s syndrome. Isr Med Assoc J 2003;5:819-820
Singaporewalla RM, Clarke MJ, Krishnan PU, Tan DE. Is this a variant of Lemierre’s syndrome?. Singapore Med J 2006; 47: 1092-1095
Goldenberg NA, Knapp-Clevenger R, Hays T, MancoJohnson MJ. Lemierre’s and Lemierre’s-like syndromes in children: survival and thromboembolic outcomes. Pediatrics 2005; 116:543-548.
Bentley T, Brennan DF. Lemierre’s syndrome: methicillinresistant Staphylococcus aureus (MRSA) finds a new home. J Emerg Med 2007; 07:66-69.
Puymirat E, Biais M, Camou F, Lefèvre J, Guisset O, Gabinski C. A Lemierre syndrome variant caused by Staphylococcus aureus. Am J Emerg Med 2008; 26,:380.e5–380.e7
Screaton N, Ravenel J, Lehner P, Heitzman ER, Flower CDR. Lemierre syndrome: forgotten but not extinct. Radiology 1999; 213: 369-374.
Fernández JL, Dones JJ, Carvajal I, Carcelén M, Gutiérrez JM, Lea MC, et al. Síndrome de Lemièrre: descripción de dos nuevos casos y revisión de la literatura. An Med Interna 2002; 19 (3):139 -142.
Bentham JR, Pollard A, Milford C, Anslow P, Pike M. Cerebral infarct and meningitis secondary to Lemierre’s syndrome. Pediatr Neurol 2004; 30:281-283.
Repanos C, Chadha N, Griffiths M. Sigmoid sinus thrombosis secundary to Lemierre syndrome. Ear Nose Throat J 2006; 85: 98 – 101.
Jones TH, Bergvall V, Bradshaw JP. Carotid artery stenoses and thrombosis secondary to cavernous sinus thromboses in Fusobacterium necrophorum meningitis. Postgrad Med J 1990; 66: 747-50.
Habek M, Petravic D, Ozretic D, Brinar V. Horner syndrome due to jugular vein thrombosis (Lemierre syndrome). J Neurol Neurosurg Psychiatry 2008; 79; 293.
Agarwal R, Arunachalam PS, Bosman DA. Lemierre’s syndrome: a complication of acute oropharyngitis. J Laryngol Otol 2000;114: 545-547
Hagelskjaer Kristensen L, Prag J. Human necrobacillosis, with emphasis on Lemierre’s syndrome. Clin Infect Dis 2000; 31:524–532
Brook I. Microbiology and management of deep facial infections and Lemierre syndrome. ORL J Otorhinolaryngol Relat Spec 2003; 65:117-120
Repanos C, Chadha N, Griffiths M. Sigmoid sunus thrombosis secundary to Lemierre´s syndrome. ENT –Ear, Nose and Throat journal 2006; 85(2): 98 -101.
Bliss S, Flanders S, Saint S. A pain in the neck. N Engl J Med 2004; 350:1037-1042.
Hochmair M, Valipour A, Oschatz E, Hollaus P, Huber M, Burghuber OC. From a sore throat to the intensive care unit: the Lemierre syndrome. Wien Klin Wochenschr 2006; 118:243–246.