Toxicity by Neonicotinoids: Two Case Reports and Topic Review
Article Sidebar
How to Cite
This work is licensed under a Creative Commons Attribution 3.0 Unported License.
Downloads
Societal impact
Main Article Content
Abstract
Pesticide poisoning is the second cause of poisoning in Colombia. Neonicotinoids are a new group of insecticides that act through nicotinic receptors. The main clinical manifestations that have been associated with such poisoning are neurological and autonomic disturbances. In this paper, we present two cases in which two patients ingested thiamethoxan and imidacloprid, showing neurologic compromise and affecting their vital signs, requiring management in the intensive care unit. The aim of this article is to raise awareness about the growing use of such pesticides and identify the need to make a differential diagnosis with other insecticides, making appropriate use of diagnostic aids and appropriate initial management of the airway and correcting the abnormalities in their hemodynamic profile to prevent complications.
Article Details
References
Boletín epidemiológico semana 21.pdf [Internet]. [Fecha de acceso 1 de diciembre de 2015]. Disponible en: http://www.ins.gov.co/boletin-epidemiologico/Boletn%20 Epidemiolgico/2015%20Boletin%20epidemiologico%20semana%2021.pdf
Mohamed F, Gawarammana I, Robertson TA, Roberts MS, Palangasinghe C, Zawahir S, et al. Acute human self-poisoning with imidacloprid compound: a neonicotinoid insecticide. PloS One. 2009; 4(4): e5127.
Phua DH, Lin CC, Wu M-L, Deng J-F, Yang C-C. Neonicotinoid insecticides: an emerging cause of acute pesticide poisoning. Clin Toxicol Phila Pa. 2009; 47(4): 336-341.
Tomizawa M, Casida JE. Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol. 2005; 45: 247-268.
Shadnia S, Moghaddam HH. Fatal intoxication with imidacloprid insecticide. Am J Emerg Med. 2008; 26(5): 634.e1-4.
Simon-Delso N, Amaral-Rogers V, Belzunces LP, Bonmatin JM, Chagnon M, Downs C, et al. Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites. Environ Sci Pollut Res Int. 2015; 22(1): 5-34.
Lin P-C, Lin H-J, Liao Y-Y, Guo H-R, Chen K-T. Acute poisoning with neonicotinoid insecticides: a case report and literature review. Basic Clin Pharmacol Toxicol. 2013; 112(4): 282-286.
Karatas AD. Severe central nervous system depression in a patient with acute imidacloprid poisoning. Am J Emerg Med. 2009; 27(9): 1171.e5-7.
Imamura T, Yanagawa Y, Nishikawa K, Matsumoto N, Sakamoto T. Two cases of acute poisoning with acetamiprid in humans. Clin Toxicol Phila Pa. 2010; 48(8): 851-853.
David D, George IA, Peter JV. Toxicology of the newer neonicotinoid insecticides: imidacloprid poisoning in a human. Clin Toxicol Phila Pa. 2007; 45(5): 485-486.
Agarwal R, Srinivas R. Severe neuropsychiatric manifestations and rhabdomyolysis in a patient with imidacloprid poisoning. Am J Emerg Med. 2007; 25(7): 844-845.