Nefropatía por Iga: la principal glomerulonefritis primaria del mundo

Contenido principal del artículo

Andrés Eduardo Toro Montoya
Cristian Camilo Benítez Restrepo
Lina María Martínez Sánchez

Resumen

La Nefropatía por IgA es una patología glomerular proliferativa mesangial, mediada por complejos inmunes, generada por el depósito de globulina tipo A; se considera la primera causa de glomérulonefritis primaria en el mundo. Se calcula que afecta al 1.3% de la población. Su incidencia es variable, pues se estima así: en Asia 29%, en Australia 12%, en Europa 10% y en Estados Unidos 10-15%. Es más frecuente en hombres que en mujeres con relación 6:1 a 10:1 y se presenta, principalmente, entre los 16 a los 40 años. Es una glomerulopatía que tiene curso clínico variable y que puede conducir a Insuficiencia Renal Terminal, con la consecuencia social y económica que ello implica. Actualmente, se tiene mayor conocimiento sobre su evolución, factores de riesgo para el desarrollo de falla renal terminal y nuevas alternativas terapéuticas. Por ellos, es importante establecer en este tipo de pacientes sus características clínicas e histopatológicas para determinar el comportamiento de la población con este diagnóstico y definir el manejo más adecuado, tanto en forma individual como colectiva.

Palabras clave:
Glomerulonefritis por IgA pronóstico enfermedades del riñón proteinuria

Citas

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Detalles del artículo

Biografía del autor/a

Andrés Eduardo Toro Montoya, Universidad Pontificia Bolivariana

Estudiante de Medicina de la Universidad Pontificia Bolivariana, Semillero de Investigación Facultad de Medicina (SIFAM).

Cristian Camilo Benítez Restrepo, Universidad Pontificia Bolivariana

Docente Titular de la Facultad de Medicina de la Universidad Pontificia Bolivariana, SIFAM.

Lina María Martínez Sánchez, Universidad Pontificia Bolivariana

Bacterióloga, Esp. en Hematología y Banco de Sangre. Coordinadora Semillero de Investigación de la Facultad de Medicina (SIFAM). Profesora Titular Universidad Pontificia Bolivariana.